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Future research, driven by advanced models, biomarker development, and clinical trials, will pave the way for innovative treatments that balance modulation of angiogenesis with preservation of neuronal homeostasis

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Neuroreport 14 , 755758 (2003)

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Zhang H, Ryu D, Wu Y, Gariani K, Wang X, Luan P, Damico D, Ropelle ER, Lutolf MP, Aebersold R (2016) NAD + repletion improves mitochondrial and stem cell function and enhances life span in mice

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In kidney aging studies, it protected renal tubular epithelial cells, reduced renal inflammation, and improved renal function

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