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Certain chemotherapeutic agents and targeted therapies, including BRAF inhibitors, can indirectly induce pyroptosis or necroptosisforms of immunogenic cell deaththereby amplifying antitumor immune responses when combined with ICIs
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However, 6-month supplementation with L-arginine in patients with peripheral arterial disease (3 g/d, n = 66, age 73 9) does not increase NO synthesis or improve vascular reactivity vs
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