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Take ibuprofen with food and water to help with anticipated discomfort

Research has shown that catechins antioxidant activity is linked to an increase in serum levels of antioxidant enzymes such as catalase (CAT), glutathione peroxidase (GSH-Px), and superoxide dismutase (SOD), alongside a reduction in malondialdehyde (MDA) formation, which is a byproduct of lipid peroxidation and a marker of oxidative stress [129]

This systemic effect may explain why users sometimes report benefits beyond the specific area being treated

If you are new to both, introduce them one at a time with at least four weeks between introductions so you can identify the source of any reaction