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The histopathological hallmarks of ALD include steatosis, hepatocyte ballooning, and neutrophil infiltration (Stickel et al., 2017), mirrored biochemically by elevated serum transaminases, dyslipidemia, diminished antioxidant enzyme activities, and increased pro-inflammatory cytokines (Li et al., 2025)

GSTP1 expression may predict the pathological response to 5-fluorouracil/epirubicin/cyclophosphamide in estrogen receptor (ER)-negative tumors (80)

With repeated administrations leading to a buildup effect

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