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Functional MRI studies link increased KYNA to reduced prefrontal activity, supporting its role in NMDAR hypofunction [105]
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Interestingly, a study found that a short-term modified fasting regimen in middle-aged individuals reduced sleep arousals and periodic leg movements
In vivo kinetics of thymidylate synthetase inhibition of 5-fluorouracil-sensitive and -resistant murine colon adenocarcinomas
