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112 Zinc Zinc is a micronutrient involved in numerous biological processes and found throughout the body

10.1016/j.pnpbp.2016.09.004 46 DeanO

Many treatment strategies for AF were established, but do not target the underlying causes of AF

Combinative treatment of -elemene and cetuximab could induce ferroptosis of KRAS-mutant colorectal cancer cells (CRC) by iron-dependent ROS accumulation, GSH depletion, lipid peroxidation, upregulation of HO-1 and transferrin, and downregulation of negative regulatory proteins for ferroptosis (GPX4, SLC7A11, FTH1, glutaminase, and SLC40A1), thus inhibiting tumor growth and lymph node metastases in vivo ( Curcuma zedoaria [Zingiberaceae
