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ROS plays a role in cancer progression, promoting various cellular processes despite causing mutagenesis

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Research has demonstrated that the accumulation and deposition of MSU crystals in the joint cavity can enhance oxidative stress, releasing large quantities of oxidants such as ROS, nitric oxide (NO) and malondialdehyde (MDA), while suppressing the activity of antioxidants such as superoxide dismutase (SOD) and glutathione (GSH)