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For example, mitophagy mediated MQC heavily depends on efficient lysosome degradation, whose dysregulation reversely suppresses mitochondrial function, so they all interplay by each other to form a vicious cycle, participating in the pathogenesis of neurodegenerative diseases

Akkaoui MA, Geoffroy PA, Roze E et al (2020) Functional motor symptoms in parkinsons disease and functional parkinsonism: a systematic review

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