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Upregulation of NCOA4 promotes lysosomal degradation of ferritin, leading to a sharp expansion of the intracellular labile iron pool, which provides the essential iron substrate for ferroptosis and directly lowers the threshold for ferroptosis initiation (83)

2-Styrylchromones as inhibitors of -amylase and -glucosidase enzymes for the management of type 2 diabetes mellitus

For instance, glutathione, a cofactor for glutathione peroxidase scavenges hydroxide, hypochlorous acid, and peroxinitrite, thus modulates atherosclerosis (Pastore and Piemonte, 2013)
