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Conversely, reducing the glycolytic activity in T cells, such as through inactivation of the glycolytic master regulator HIF-1, promotes a shift in CD8 T cells towards greater reliance on mitochondrial respiration, thereby enhancing their stemness during chronic viral infection [18]

Symptoms typically include fatigue, depression, irritability, increased appetite, and hypersomnia

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176 Before the development of statin drugs, niacin was commonly used to treat abnormal lipid profiles
