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Description

While many of the current studies investigating the effects of SCT on neurodegenerative disorders employ different protocols and cell types, most of them point to neuroprotection mediated by brain-derived neurotrophic factor (BDNF), glial cell line-derived neurotrophic factor (GDNF), or nerve growth factor (NGF) [25], as shown in Fig

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This activation: Promotes directed cell migration toward injury sites Enhances cellular outgrowth from damaged tissue edges Improves cell survival during the stressful healing process Facilitates proper tissue organization This mechanism is particularly relevant for tendon and ligament healing, where cellular organization and proper fiber alignment are critical for functional recovery