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Description
Proteotoxic stress A cellular condition caused by the accumulation of misfolded, aggregated or damaged proteins, overwhelming the protein quality control systems and disrupting normal cellular function
Brain Behav Immun (2019) 80:1639
Anti-diabetic effect of watermelon ( Citrullus vulgaris Schrad) on streptozotocin-induced diabetic mice
The study's lead compound, 75 , showed satisfactory inhibition against XO with an IC 50 value of 0.20 nM, which was higher than febuxostat and topiroxostat (Figure 24)
