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Patients should stop tirzepatide and seek immediate medical care if they experience severe, persistent abdominal pain (which may indicate pancreatitis), symptoms of gallbladder disease (right upper quadrant pain, fever, jaundice), persistent vomiting leading to dehydration (which may cause acute kidney injury), or signs of severe allergic reaction
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Pinch the skin at the injection site between your thumb and forefinger to create a fold of tissue about one to two inches wide
