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Acknowledgements We would like to thank Bruce Wolffenbuttel and Andrew McCaddon for their advice and assistance of this perspective
By supporting mitochondrial function and protecting against oxidative damage, glutathione injections may help improve cellular energy production and overall vitality
We showed that extra-mitochondrial WT PINK1 inhibit tyrosine hydroxylase (TH) and down regulate DA level in DA neurons, whereas pathogenic PINK1 mutations up-regulate TH activity and DA content in DA neurons
Kaplowitz N (2005) Idiosyncratic drug hepatotoxicity
