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Fibroblast growth factor 23 and anemia in the chronic renal insufficiency cohort study

In patients with severe renal impairment (CL crless than 30 mL/min/1.73 m 2) not on hemodialysis, the recommended starting dosage is 5 mg once daily and should not exceed 10 mg once daily [see Warnings and Precautions (5.1)and Use in Specific Populations (8.6)]

The systemic administration of ferroptosis inhibitors raises concerns about off-target effects, particularly the suppression of anti-tumor immunity, given the role of ferroptosis in immune surveillance

R., & Bhoyar, L
