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Similarly, one-carbon metabolism is enhanced in cancer cells to support purine and pyrimidine synthesis and methylation reactions [12,13]
Panicker, A.K
Complex structural rearrangements are present in high-grade dysplastic Barretts oesophagus samples

Several questions arise and will drive further work, the first concerns on experimental evidence for our hypothesis: given a group with phytopathogens and nonpathogens close members, would the introduction of a nirS gene cluster in the latter be necessary and sufficient to convert them in disease agents to a specific host