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Furthermore, metformin regulates fatty acid (FA) synthesis through the AMPK/SREBP-1 pathway, thereby reducing the likelihood of malignant transformation in cancer cells (Zhou et al., 2024

Minimal Heat Cooking If cooking is necessary, use low to medium heat for a short duration to retain more glutathione

doi: 10.1016/j.celrep.2021.110019 99 KeeneC

These data therefore establish biochemical proteinaceous signatures for the inner layer ( e.g ., RAB7, SNX3, and various cargo proteins) and outer layer ( e.g ., TBC1D5, ANKRD27, DNAJC13 and the WASH complex) of the Retromer coat complex and/or those proteins transiting through the Retromer retrieval sub-domain