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There is After having a B12 shot, a person should monitor for adverse symptoms and seek medical help if they experience: severe pain at the injection site mild diarrhea a swelling sensation in the body temporary itching of the skin In rare cases, a person may also be at risk of: anaphylaxis pulmonary edema congestive heart failure peripheral vascular thrombosis, which involves blood clots polycythemia vera, which is a type of blood cancer If anyone experiences difficulty breathing, hives, or swelling, they need emergency medical help

NICE guidance acknowledges that response to treatment varies between individuals

The idea is to encourage the body to break down stored fat (lipolysis) while having little effect on blood sugar or IGF-1

Tesofensine works through neurotransmitter reuptake inhibition