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Description
no proteins changed in NQO1*2 cells reinforcing the selectivity of the NQO1-bioactivatable agent IB-DNQ (Supplementary Figure 2)
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Moreover, overexpression of GPX3 further exerted anti-autophagy by inhibiting AMPK/m-TOR and up-regulated nuclear factor erythroid 2-related factor 2 (Nrf2)/glutathione peroxidase 4 (GPX4, mitochondrial GPX4 and cytoplasmic GPX4) to antagonize autophagy-related ferroptosis
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