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Typical experimental endpoints include measures of collagen and extracellular matrix protein expression, cell migration rates, cytoskeletal organization, and transcriptional changes in genes related to tissue structure and repair, depending on the model

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Similarly, a mouse model study showed that a reduction in mitochondrial DNA polymerase g (POLG) is linked to higher levels of mutations and more apoptotic markers relative to the control group with intact POLG expression levels (Lee and Wei, 1997

[DOI] [PubMed] [Google Scholar] 15.Lee E, Padgett B: Intra-articular injection of BPC 157 for multiple types of knee pain