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Supplementing with riboflavin altered the DNA methylation in people with MTHFR C677T, causing a decrease in methylation of the ACE gene.[ref] Benefits of supplemental riboflavin: Clinical trial data Clinical trials are an excellent way to know if a supplement is effective for most people

However, Se deficiency is a global health concern, affecting over 1 billion individuals, and the production of Se-fortified crops is inevitable

*Correspondence: Kenneth B