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Still, TROP2 remains attractive: the TROPHIT-1 phase II/III trial is comparing SG vs SOC in refractory mCRC, and datopotamab deruxtecan (Dato-DXd)-a TROP2-DXd ADC with strong bystander effect-is being tested in CRC in TROPION-PanTumor03

The term "skin purging" refers to the increased cellular turnover rate caused by a reaction to an active ingredient, usually those found in products with exfoliating properties like AHAs, BHAs, or Retinols

Prescribers are rewriting prescriptions for alternative formulations mid-cycle

J Chem Technol Biotechnol
