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For example, PRMT1-mediated STAT6 methylation, induced by hypoxia-inducible factor (HIF)-1, promoted M2 macrophage polarization, contributing to fibrotic signaling in lung epithelial cells [91]
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Increased levels of DSBs were detected in AD brain neurons as well as in mice transgenic for human APP, which mimics several key aspects of AD neuropathology (54)
