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We found that retinal BF in rats, as measured with laser speckle flowgraphy, was significantly reduced 3 wk after an intravitreal injection of AAV2-human endothelin-1 (AAV2-hEDN1)

NAD + deficiency can impair the PPP's ability to produce NADPH via decreased hexokinase activity [490,491,492]

Available online: www.who.int/news/item/14-11-2023-quitting-smoking-cuts-your-risk-of-developing-type-2-diabetes-by-30-40

The expression of antioxidant protective genes and phase II detoxification enzyme genes induced by it can effectively reduce the sensitivity of liver cells to ROS and electrophiles, slow down the development of liver diseases, and prevent the occurrence and progress of liver fibrosis