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Regul Toxicol Pharmacol 137:105306
As shown in Table 1 and Figure 6, in the pursuit of structurally diverse NNMT inhibitors, researchers have identified certain macrocyclic peptides that bind to NNMT, displaying potent inhibition with Half-maximal inhibitory concentration (IC 50 ) values as low as 229 nM (Van Haren et al., 2021)
Furthermore, the Nrf2 pathway induces many genes, regulating redox homeostasis, detoxification, autophagy, and DNA repair (26)
The spatiotemporal changes in dopamine, neuromelanin and iron characterizing parkinsons disease
