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[DOI] [PMC free article] [PubMed] [Google Scholar] 131.Beloglazova N., Speranskaya E.S., Wu A., Wang Z., Sanders M., Goftman V.V., De Saeger S

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The design of a ligand requires several steps to fulfil [2]: Determination of the binding site or possible biological interactions to use as a template for the modelling, Initial design of the ligand using this template, Preparation of a ligand library and chromatographic evaluation, Selection of the ligand of interest, Optimisation and chromatographic evaluotion of the adsorbent following the immobilization