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Dev Neurosci 40(56):382395
Initially discovered in the endoplasmic reticulum, HO-1 has also been detected in mitochondria, nuclei, and follicles in subsequent studies
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189 In an uncontrolled trial that included 119 men with idiopathic infertility, supplementation with a multi-nutrient cocktail containing vitamins, minerals, and several antioxidants twice daily for three months led to significant improvements in sperm concentration, motility, morphology, and DNA fragmentation compared with pretreatment analyses
