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Furthermore, second O 2 and proton bind to the reduced form of the enzyme (Fe 2+ , Cu + , and Mn 2+ ), which results in liberating H 2 O 2 and returning of enzyme to its oxidized form [19, 21]

Crotonylation As a final PTM, let's take a brief look at crotonylation

10.1128/mr.59.4.604-622.1995 27 NakayamaH.YoshidaK.OnoH.MurookaY.ShinmyoA

Second-line treatments have also been designed over the past few years, including regorafenib (antiangiogenesis) (Zhu et al., 2019)
