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Description
The operational calculus is becoming straightforward: hybrid models reduce screen-failure rates by extending geographic reach while preserving investigator oversight over critical procedures, delivering a patient enrollment advantage that translates directly into shortened study timelines and reduced per-patient cost

Endocrinology 158 , 26802693 (2017)

While you should probably leave the imitation crab meat for things like crab rangoon, there are a fair number of decent options to choose from
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