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Failing the test or refusing it can lead to immediate penalties

Specifically, the compounds extensive biological activity should inherently entail an irreducible risk of unanticipated off-target or systemic adverse effects [1]

Pyridoxine (B) in high doses is known to interact with certain drugs: it can reduce the therapeutic efficacy of levodopa by increasing peripheral conversion of levodopa to dopamine (vitamin B speeds up decarboxylation)