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This biotransformation is catalyzed by UDP glucuronosyltransferases (UGT), located in the endoplasmatic reticulum, which transfer a glucuronic acid from a uridine 5 2-diphosphoglucuronic acid (UDPGA) cofactor to a functional group or phase I metabolite, forming a glucuronide conjugate (Figure 8)

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Folkers K, Langsjoen P, Willis R, Richardson P, Xia LJ, Ye CQ, Tamagawa H

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