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Specifically, recent research has suggested a bidirectional communication between metabolic dysfunction (loss of metabolic homeostasis) and cellular senescence (67, 68)

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[DOI] [PMC free article] [PubMed] [Google Scholar] 99.Hou TT, Han YD, Cong L, Liu CC, Liang XY, Xue FZ, Du YF

It may be secondary to fatigue, dyspnoea, medication toxicity or unpalatable diets
