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GDF15 seems to be necessary for allergen avoidance, yet it is incapable of driving avoidance alone at concentrations comparable to the allergen challenge, suggesting that other signals may synergize with GDF15 to promote avoidance

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Modulation of tryptophan catabolism by regulatory T cells

The increase in permeability in the aging group appeared to be restricted to solutes since the permeability to macromolecules was not affected by aging [69]