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Exogen is often considered an extension of the telogen stage, signaling the natural progression of the hair growth cycle

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How the -helix weakens the catalytic efficacy is unknown

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As a matter of fact, taking into full account the intricacy of the numerous regulatory mechanisms involved in OS control as well as the complex interplay between the many events that contribute to the progressive degeneration and death of MNs, future neuroprotective pharmacological therapies will likely need to aim for an integrated treatment, acting on several levels to limit the progression of the disease

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S.DehsarviA.StewardA.et al (2025)

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