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Zhu JW, Ni YJ, Tong XY, Guo X, Wu XP

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TPO is a key enzyme in the synthesis of thyroid hormone responsible for catalytic oxidation of iodine and iodization of tyrosine, and inhibition of TPO activity can directly lead to reduced thyroid hormone synthesis (Godlewska and Banga, 2019)
A maximal locomotor effect resulted from 0.75 mg/kg METH in male rats, which was comparable to 0.32 mg/kg in females
