cf and glutathione The influence of diminished transport on the CF Foundation | Therapeutics Pipeline
Description
Ann Shippy That's correct
"Identification of a novel putative non-selenocysteine containing phospholipid hydroperoxide glutathione peroxidase (NPGPx) essential for alleviating oxidative stress generated from polyunsaturated fatty acids in breast cancer cells"
Specifically, p66Shc can generate ROS through the oxidation of cytochrome c by utilizing the reducing equivalents of the mitochondrial ETC, playing a crucial role in carcinogenesis and aging [44]
& Mulcahy, R
