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Comparative analysis of lipid metabolism between the HFD + EPA + L-carnitine group and the HFD group showed a significant increase in EPA (EPA was below detection limits in the HFD group), DHA and DPA and a significant decrease in arachidonate in the former group (20:4n-6) (Table 4)

Quality Assessment The methodological qualities of the included RCTs were assessed according to Cochrane Collaboration's tool described in Handbook version 5.1.0 [10]

Mitochondrial overload and incomplete fatty acid oxidation contribute to skeletal muscle insulin resistance

Adems del consumo excesivo de grasas que puede causar hgado graso, cuando hay una deficiencia de L-carnitina en el cuerpo o un suministro insuficiente de grupos metilo, se produce una alteracin en la oxidacin de los cidos grasos de cadena larga, lo que tambin lleva a una acumulacin excesiva de grasa en el hgado y, en consecuencia, a hgado graso