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Patients with severe heart failure or arrhythmias require monitoring because rapid shifts in free-fatty-acid metabolism can influence myocardial substrate utilization

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This remarkable compound possesses the ability to effectively impede the interplay between inflammation and fibrosis, ultimately suppressing the activation of succinate related NLRP3 inflammasomes and consequently preventing myofibroblast activation (59)

Refinement of intraperitoneal injection of sodium pentobarbital for euthanasia in laboratory rats (Rattus norvegicus)