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Description
In the HOPE study, supplementation of 400 IU (=268 mg) of vitamin E/day in mild to moderate CKD patients has no effect on cardiovascular outcomes and overall mortality and therefore supplementation of vitamin E is not recommended (HOPE Study Investigators, 2000)
In the presence of poor prognostic markers, insufficient response to synthetic DMARDs or intolerance, EULAR recommends shifting to any biological DMARD
[DOI] [PMC free article] [PubMed] [Google Scholar] 162.Chiechio S., Canonico P., Grilli M
10.3892/or.2020.7781 45 FilomeniG.DesideriE.CardaciS.GrazianiI.PiccirilloS.RotilioG.et al (2010)
