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IP3 and DAG act as secondary messengers and participate in downstream signaling processes ( Figure 2 Structure of different PLC isoforms In mammals, 13 different PLC isozymes have been reported and are divided into six different subfamilies, namely , , , , , and ( Figure 3 ) ( Figure 3 PH domains The N-termini of PLCs (except PLC-) have the PH domain, which consists of ~120 amino acids

Blockade of lactate transport exacerbates delayed neuronal damage in a rat model of cerebral ischemia

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