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In A549 cells, MPs determine the activation of the apoptotic mechanism via Bax, caspase 3, 8 and 9 and cytochrome C upregulation, along with cell cycle S phase arrest [93]
doi: 10.1002/micr.1920020303 33 DonskiPKFranklinJDHurleyJVO'BrienBM
Impact of selenium on biomarkers and clinical aspects related to ageing

However, the compensation of partially functioning proteins such as SHANK3, FMRP, or CHD8 during neural development would require increased metabolic activity and, subsequently, more oxidative stress
