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Description
While the -2a or isoform of OGG1 was initially presumed to be the main mitochondrial isoform [135], a recent study demonstrated that the endogenous mitochondrial-targeting sequence of the predominant -1a isoform is sufficient to target both the nucleus and mitochondria [151]
Joule 2023, 7 (8), 17451758
Cerebellum 12 , 4347 (2013)
Collectively, these data demonstrate that TLR2 contributes to IL-1 production, electrical disturbances and arrhythmias in a mouse model of DM
