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Description
Cigarette smoke reversibly activates hypoxia-inducible factor 1 in a reactive oxygen species-dependent manner

Mechanistically, IGF2BP3 destabilized CFTR mRNA (an ABC transporter), reducing 5-FU uptake

Acta Pathologica Microbiologica Scandinavica 48, 121132

It also reduces allergic reactions, lowers cancer risk, and alleviates chemotherapy side effects
