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Modulates nitric oxide (NO) signaling It influences nitric oxide synthase activity, affecting vascular tone and tissue perfusion, which is essential for delivering oxygen and nutrients to healing tissues

This same variant has been found to be enriched in heteroplasmic cultured mouse L cells (Fan et al

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From a mechanistic perspective, Mgs NMDA receptor blockade and GABAergic modulation have the capacity to attenuate excitatory stress circuits
