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The crucial function of B12 in sleep latency is reinforced by a previous study that examined the impact of vitamin B12 supplementation on the sleepwake cycle of individuals with delayed sleep phase syndrome, showing a significant temporary improvement in the supplemented group [26]

Most common side effect is mild skin irritation at the patch site

Under physiological conditions, GH is secreted in discrete pulses occurring with species-specific frequency (every 3-5 hours in humans), with pulse amplitude varying based on metabolic state, sleep stage, nutritional status, and other factors