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We pairwise matched the sub-groups, and both cohorts had similar demographic and clinical characteristics other than length of response, allowing us to study CAR T cell functionality without potential confounding variables such as antigen escape and post CAR T cell consolidation therapies (Table 1, Supplementary Data 1)

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Additionally, measuring real-time redox changes poses a significant challenge for future studies, as ROS and antioxidants operate on very short timescales and in localized cellular compartments, requiring highly specialized techniques for accurate assessment

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