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Research indicates that an imbalance between free radicals and antioxidants can lead to endothelial dysfunction, a condition where the inner lining of blood vessels doesn't function correctly
The number of glutathione injections varies by individual needs
In Phase I/II combination study with irinotecan and cetuximab in selected patients with KRAS WT locally advanced or mCRC (NCT01075048), the addition of tivantinib did not improve PFS, the primary endpoint (Eng et al., 2016)
This, however, increases the molecular targets that can be therapeutically tackled to control bacterial infections 108
