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When swelling lasts more than 24 hours , keeps returning, or gets more painful instead of better, that is a sign to stop guessing and get evaluated

Therefore, evaluating the efficiency of microbiota-remodeling strategies, predominantly pro/pre/synbiotic therapy, on obesity and metabolic comorbidities has come into focus (24, 25)

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Data collection We collected demographic and clinical data at baseline (El Escorial category, date of disease onset and diagnosis, site of onset), medical/surgical history, including comorbidities, physical and neurological examination
