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It is of note that ROS levels did not increase during p16 induction of growth arrest (Figure 4D)
[DOI] [PMC free article] [PubMed] [Google Scholar] 182.Fonseca SB, Pereira MP, Mourtada R, Gronda M, Horton KL, Hurren R, Minden MD, Schimmer AD, Kelley SO
IGF-1 levels were observed to potentially increase by about 28%, which may indicate improved functionality of the growth hormone and IGF-1 axis
