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Anti-apoptotic protein upregulation Bcl-2 family regulation: Balance between pro-apoptotic (Bax, Bad, Bid) and anti-apoptotic (Bcl-2, Bcl-xL, Mcl-1) Bcl-2 family members determines cell survival versus death

All dosages of danuglipron significantly reduced patients HbA1c and fasting blood glucose levels, with more pronounced weight loss effects observed in the 80 mg and 120 mg doses compared to the placebo group
( ) NNMT NAD- NAD ( 40+)

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